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Oral health care considerations for patients with peptic ulcer disease:

  • Minimize stress, which may exacerbate symptoms of the disease.
  • Avoid medication that may exacerbate or cause gastric ulceration, such as aspirin and NSAIDs.
  • Be aware of the reduction in the efficacy of antibiotics, such as erythromycin and tetracycline, if they are given within 1 hour of antacids containing calcium, magnesium, or aluminum salts.
  • Address potential anemia if there is a recent history of perforation.
  • Address oral dryness due to medications if present.
  • Palatal enamel erosion should be restored.
  • Treat major aphthous stomatitis when present.

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